Role of clusters in insulin-regulated GLUT4 trafficking in adipose cells: A new paradigm?
نویسنده
چکیده
Insulin stimulates glucose transport in muscle and adipose cells by stimulating translocation of glucose transporter 4 (GLUT4) to the plasma membrane. In a recent Cell Metabolism paper, Stenkula et al. found that insulin controls the spatial distribution of GLUT4 on the surface of isolated adipose cells through regulation of their post-fusion dispersal. The presence of GLUT4 in plasma membrane-associated clusters is suggestive of a new paradigm in membrane protein recycling.
منابع مشابه
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2010